What is the radiation dose tolerance of the cochlea according to QUANTEC for fractionated radiation therapy?
Central Nervous System
General CNS
No
U
C
Per QUANTEC recommendations (Bhandare et al. IJROBP 2010), to minimize the risk of hearing loss the mean cochlea dose (whole organ) should be kept ≤45Gy, or more conservatively ≤35Gy, for patients undergoing standard fractionation. This corresponds to a risk of sensorineural hearing loss of < 30%.
For patients undergoing SRS for vestibular schwanomma, the prescription dose should be limited to 12-14 Gy for hearing preservation.
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